HCR hairpin NUPACK is a growing software suite for the analysis and design of nucleic acid systems.

NUPACK currently enables:

  • thermodynamic analysis of dilute solutions of interacting nucleic acid strands in the absence of pseudoknots or of non-interacting strands with the possibility of a class of pseudoknots
  • thermodynamic design based on simultaneous affinity and specificity optimization for a single-stranded, unpseudoknotted secondary structure

You are welcome to submit jobs and inspect results using the NUPACK web server or to download NUPACK source code for research purposes.

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