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Analysis
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NUPACK is a growing software suite for the analysis and design of nucleic acid structures, devices, and systems.

The NUPACK web application enables analysis and design of the equilibrium base-pairing properties of one or more test tubes of interacting nucleic acid strands:

NP-testtubes

Please cite the web application and algorithms appropriately; usage statistics are an important component in helping to secure funding for NUPACK development.  We are happy to provide advice and technical support.

— The NUPACK Team

News: The all-new NUPACK 4 Python module is available for download! The new unified dynamic programming framework offers: 1) enhanced physical models (coaxial and dangle stacking); 2) dramatic speedups (20-120x for test tube analysis); 3) overflow-safe evaluation algebras for large complexes (e.g., 30,000 nt). (unified framework paper, supp info, download, user guide)
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